
the major concern with mtf hrt is long-term impact on fertility. there isn’t any/good data on how often it causes infertility. some people were infertile before starting hrt, some are infertile after hrt, and some regain their fertility by going off of hrt. if you’re able to make peace with that risk and/or bank sperm; just trying hrt can be one of the best ways to figure out if it’s right for you. the major non-reversible effect of e is breast growth, which is very gradual.
There are sexual side effects like loss of fertility, balls shrinking, difficulty getting erect, loss of libido, and orgasms feeling different. But for many trans women, these are either irrelevant or even euphoric. The other side effects would be that there can be pain, such as swollen or tender breasts and abdominal pain. And you also temporarily lose muscle mass, bone density, and fat. But they get redistributed.