
For most guys, the immediate interest is not sexual. you should focus on getting someone interested in you generally and not try to push things in a sexual direction. guys detecting a slight amount of interest and immediately making the conversation sexual is a huge turn off and it happens all the time.
Bro there's no one size fits all answer to approach any girl in any situation. It isn't a textbook with correct answers. That's why I said be confident and charming and funny, those are attributes that help you figure out what to say in the moment. If you come in with pickup lines at the ready then it's always going to seem insincere/creepy